TB-500 is a synthetic version of a key active fragment of Thymosin Beta-4 (TB4), a ubiquitous actin-sequestering protein present in all nucleated cells. In research settings, TB-500 is used to study cellular migration, angiogenesis, tissue repair modeling, and actin polymerization dynamics. Its preclinical literature spans cardiovascular biology, musculoskeletal research, and wound biology models. Helix Strand Labs supplies TB-500 in lyophilized form with verified purity for laboratory use.
Research Applications
- Actin regulation and cytoskeleton biology research
- Cell migration and motility modeling
- Angiogenesis and cardiovascular biology studies
- Tissue repair and wound biology preclinical models
- Inflammation pathway research
| Classification | Thymosin Beta-4 Synthetic Analog |
| Molecular Weight | ~4963 g/mol |
| Purity | ≥98% (HPLC verified) |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
| Storage & Stability | Lyophilized powder. Store at -20°C. Stable 24 months sealed. After reconstitution, refrigerate at 2–8°C and use within 14 days. |
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